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Abstract: . . . research grants program, the Society currently (July 2001) funds 184 research projects relating to breast cancer totaling almost $62 million. A few areas of research now being investigated by American Cancer Society grantees are: • Anti-angiogenesis drugs that block the supply of new blood vessels to breast tumors • How differences in the ability to metabolize alcohol influence breast cancer risk • How a woman’s genetic makeup determines her response to treatment • New molecular targets for anticancer dr . . . . . . almost $62 million. A few areas of research now being investigated by American Cancer Society grantees are: • Anti-angiogenesis drugs that block the supply of new blood vessels to breast tumors • How differences in the ability to metabolize alcohol influence breast cancer risk • How a woman’s genetic makeup determines her response to treatment • New molecular targets for anticancer dr . . . . . . more representative clinical trials. • to gain fuller understanding of mechanisms underlying behavioral change, and identify how psychosocial factors influence disease response and survival. • to better understand the effects of multimodal treatments, and improve methods to study patient-focused outcomes across the continuum of age and race/ethnicity. Page 17 Breast Cancer Facts & Figures 15 researchers to design rational therapeutics that may have greater efficacy and fewer side effects than con- ventional chemotherapy. Forty to 50 anti-angiogenesis compounds, drugs that starve the tumor of the blood it needs in order to grow, are in development for breast cancer . 46 Metronomic therapy, a relatively new concept in anti-angiogenic therapy, uses . . . . . . representative clinical trials. • to gain fuller understanding of mechanisms underlying behavioral change, and identify how psychosocial factors influence disease response and survival. • to better understand the effects of multimodal treatments, and improve methods to study patient-focused outcomes across the continuum of age and race/ethnicity. Page 17 Breast Cancer Facts & Figures 15 researchers to design rational therapeutics that may have greater efficacy and fewer side effects than con- ventional chemotherapy. Forty to 50 anti-angiogenesis compounds, drugs that starve the tumor of the blood it needs in order to grow, are in development for breast cancer . 46 Metronomic therapy, a relatively new concept in anti-angiogenic therapy, uses much . . . --3000,4,375,2697,51450
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