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Abstract: . . . environmental pollutants. Environ Health Perspect 103:113–122. [US CDCP] US Centers for Disease Control and Prevention. 1997. Public Health Statement for Vinyl Chloride, CAS 75-01-4. Agency for Toxic Substances and Disease Registry, USA. Warner M, Eskenazi B, Mocarelli P, Gerthoux PM, Samuels S, Needham L, et al. 2002. Serum dioxin concentrations and breast cancer risk in the Seveso Women’s Health Study. Environ Health Perspect 110:625–628. Wolff MS, Collman GW, Barrett JC, Huff J. 1996. Breast cancer and environmental risk factors: epidemiological and experimental findings. Annu Rev Pharmacol Toxicol 36:573–596. Page 13 13 Appendix 1: Some chemicals associated with increased incidence of mammary tumours in rats and/or mice Chemical Use Pesticides atrazine herbicide clonitralid molluscicide 1,2-dibromo-3-chloropropane a soil fumigant 1,2-dibromoethane a soil fumigant; lead scavenger in petrol 1,2-dichloropropane (propylene dichloride) fumigant; chemical intermediate; solvent in drying cleaning fluids . . . . . . products. Am J Ind Med 37:349–352. Page 11 11 Hodgen E, Tobias M, Cheung J. 2002. Cancer in New Zealand: Trends and Projections . Public Health Intelligence Occasional Bulletin Number 15. Ministry of Health, Wellington. Hoyer AP, Grandjean P, Jorgensen T, Brock JW, Hartvig HB. 1998. Organochlorine exposure and risk of breast cancer . Lancet 352:1816–1820. Hoyer A, Jorgensen T, Grandjean P, Hartvig H. 2000. Repeated measurements of organochlorine exposure and breast cancer risk (Denmark). Cancer Causes Control 11:177–184. [IARC] International Agency for Research on Cancer 1999. Overall Evaluations of Carcinogenic Risks to Humans . IARC Monographs. International Agency for Research on Cancer , Lyon. Available: http://193.51.164.11/mono-eval/crthall.html. Jobling S, Reynolds T, White R, Parker MG, Sumpter JP. 1995. A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environ Health Perspect 103:582–587. Korach KS, McLachlan JA. 1995. . . . . . . diisocyanate a in manufacture of flexible polyurethane foams 1,2,3-trichloropropane a chemical intermediate; former solvent and paint remover vinyl chloride manufacture of PVC, hazardous waste, landfills, cigarette smoke vinyl fluoride a = listed in 9 th Report on Carcinogens as “reasonably anticipated to be a human carcinogen b = listed in 9 th Report on Carcinogens as “known human carcinogen” c = listed in 9 th Report on Carcinogens as “known human carcinogen” with some epidemiological evidence of breast cancer Sources: Cabello et al 2001; DeBruin & Josephy 2002; Brody & Rudel 2003. Page 15 15 Appendix 2: Selected endocrine disruptors Chemical Use Pesticides atrazine herbicide chlordane insecticide chlorpyrifos insecticide cypermethrin insecticide 2,4-D herbicide DDT (and associated compounds) insecticide dieldrin, aldrin, endrin insecticides lindane insecticide; hair treatment for lice malathion insecticide methoxychlor insecticide; veterinary pharmaceutical pentachlorophenol wood preservative . . . --3000,3,500,3256,35514
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