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Abstract: . . . to be confirmed. REFERENCES 1. Olsen, J. H., Boice, J, D., Jensen, J. P, A., and Fraumeni, J. F, Cancer among epileptic patients exposed to anticonvulsant drugs, J. Natl. Cancer Inst., 81: 803-808, 1989, 296 Page 4 ANTIEPILEPTICS AND HUMAN CANCER 2. Olsen, J. H., Andersson, M., and Boice, J. D. Danish epileptics given Thorotrast. In: D. M. Taylor, C W. Mays G. B. Gerber, and R. G. Thomas (eds.) Risk from Radium and Tborotrast . . . . . . lymphomas to specific anticonvulsants. In conclusion, our findings indicate that the increased risk for cancers of the liver and biliary tract among Danish epileptic patients are due to factors other than anticonvulsant treatment, including Thorotrast administration and conditions related to cirrhosis of the liver. Phenobarbital then appears to be of little importance in the etiology of these tumor types in humans. The study was large, . . . . . . 1989. White, S. J., McLean, A. E. M., and Howland, C. Anticonvulsant drugs and cancer: a cohort study in patients with severe epilepsy. Lancet, 2: 458-460, 1979. Shirts. S. B. , Annegers. J. F. Hauser. W. A. and Kurland, L. T. Cancer incidence in a cohort of patients with seisrre disorders. J. Natl. Cancer Inst., 77: 83-87, 1986. 297 . . . . . . 1624-1633, 1963. van Kaick, G., Wesch, H., Lührs, H., Liebermann, D., Kaul, A., and Muth, H. The German Thorotrast Study–report on 20 years follow-up. In: D. M. Taylor, C. W. Mays, G. B. Gerber, and R. G. Thomas (eds.), Risk from Radium and Thorotrast, pp. 98–104. London: British Institute of Radiology (BIR Report no. 21), 1989. White, S. J., McLean, A. E. M., and Howland, C. Anticonvulsant drugs and cancer: a cohort study in patients . . . . . . 1990. Cabral, J. R. P., MacMahon, B., and Saracci, R. Phenobarbital. In: N. J. Wald and R. Doll (eds.), Interpretation of Negative Epidemiologic Evidence for Carcinogencity, pp. 151–160. Oxford, United Kingdom: oxford University Press, 1985. McClain, R. M. Mouse liver tumors and microsomal enzyme-inducing drugs: exper- imental and clinical perspectives with phenobarbital. In: D. E. Stevenson R. M. McClain J. A. Popp., T. J. . . . . . . lymphoma Page 1 [CANCER RESEARCH 55, 294-297, January 15, 1995] Antiepileptic Treatment and Risk for Hepatobiliary Cancer and Malignant Lymphoma Jørgen H. Olsen, 1 Gabi Schulgen, John D. Boice, Jr., John Whysner, Lois B. Travis, Gary M. Williams, Frank B. Johnson, and James 0'D. McGee Division for Cancer Epidemiology, . . . . . . a cohort study in patients with severe epilepsy. Lancet, 2: 458-460, 1979. Shirts. S. B. , Annegers. J. F. Hauser. W. A. and Kurland, L. T. Cancer incidence in a cohort of patients with seisrre disorders. J. Natl. Cancer Inst., 77: 83-87, 1986. 297 . . . --3000,7,214,3118,24783
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